Does a powder containment hood – not an ISO 5 hood – used for sterile compounding have to be externally vented?
No. Assuming the powder containment hood is for the non-sterile preparation of a sterile compound, it can be vented into the room via redundant HEPA filtration. The hood is still required to be in a C-SEC, which is vented to the outside.
|API||Active pharmaceutical ingredient|
|CACI||Compounding aseptic containment isolator|
|C-PEC||Containment primary engineering control|
|C-SEC||Containment secondary engineering control|
|HEPA||High-efficiency particulate air|
|NIOSH||National Institute for Occupational Safety and Health|
|SOP||Standard operating procedure|
- US Pharmacopeial Convention. (2016). Frequently Asked Questions: <800> Hazardous Drugs—Handling in Healthcare Settings. Retrieved from http://www.usp.org/frequently-asked-questions/hazardous-drugs-handling-healthcare-settings