PCCA Lipoderm®
The Only Proven Transdermal Method of Delivering Up to Four Medications, Simultaneously
Gus Bassani Explains Breakthrough PCCA Lipoderm Study
PCCA's VP of Research & Development, Gus Bassani, presents the latest information on Lipoderm, a transdermal base clinically proven to deliver drugs through a patient's skin. Lipoderm -- your medications in a cream!
Product Overview - Lipoderm Transdermal Bases
Available exclusively from PCCA, the Lipoderm family of transdermal bases was independently tested, using the Franz Skin Finite Dose Model, and proven to deliver up to four drugs simultaneously through human skin in vitro. Lipoderm also was tested for allergic reactions – no adverse reactions were reported in an extensive two-month study. The Lipoderm family includes:
Lipoderm is an elegant alternative to traditional pluronic lecithin organogels (PLO) and contains a proprietary liposomal component that may increase the permeation of a variety of actives. Its touch and feel is smooth and creamy, unlike the tacky feel of PLOs. Many members have made the switch to Lipoderm for their transdermal needs because it is a stable system that does not separate upon refrigeration and has great resiliency in the presence of ionic substances.
Lipoderm® Transdermals Keep Delivering... But Don’t Take Our Word for It.

Even the latest competitive study proves that Lipoderm Transdermal absorbs better and faster.
Even when compared to the newest competitive studies, Lipoderm Transdermal base can deliver Ketoprofen more quickly and with better absorption. Not only does it deliver Ketoprofen more effectively, it also delivers up to four actives simultaneously – with the studies to prove it.
Lipoderm ActiveMax™ has the benefits of original Lipoderm with an added stabilizing system to provide resiliency in the presence of high salt loads. How do you know when/if you need Lipoderm ActiveMax? If you are using over 20% actives in a formula and experiencing separation or liquification. For example, 30% Ketamine HCl in Lipoderm ActiveMax demonstrated superior physicochemical attributes, remaining stable and elegant for six months.
Anhydrous Lipoderm utilizes similar technology to the well-studied and popular base, Lipoderm, and is an anhydrous version for actives that are unstable in water. It is also free of gluten, casein, egg, wheat-germ, paraben, butylated hydroxytoluene (BHT) and soy. This base utilizes rapeseed-based phospholipids, and may provide a better alternative for autistic patients than traditional Lipoderm. It also has a neutral odor and silky feel.
Lipoderm High Molecular Weight™, the latest in transdermal technology, is focused on the delivery of large molecular weight proteins. Lipoderm HMW does not contain lecithin, phospholipids or eggs, and could be an appropriate choice for autistic patients. This base has a low resiliency for salt forms of drugs, which cause the base to break.
See the results of clinical studies performed on Lipoderm!
PCCA Lipoderm® Delivers Four Drugs Simultaneously in Transdermal Study
Lipoderm® Proven to Deliver Ketamine HCl, Gabapentin, Clonidine HCl and Baclofen Simultaneously Through Human Skin In Vitro – FIRST STUDY OF ITS KIND
PCCA Lipoderm® Feline Vet Study
Lipoderm with Tramadol Performs Well in Feline Inner Ear Test
PCCA Lipoderm® and Ketoprofen Transdermal Study
PCCA Lipoderm now PROVEN to Deliver the NSAID Ketoprofen Through Human Skin In Vitro
PCCA Lipoderm® and Promethazine Transdermal Study
PCCA Lipoderm now PROVEN to Deliver the NSAID Ketoprofen Through Human Skin In Vitro